2 datasets found

Licenses: License not specified Tags: cardiotoxicity

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  • hERG inhibition leading to cardiac toxicity

    hERG channel blockade leading to sudden cardiac death Increased mortality triggered by drug-mediated blockade of human ether-a-gogo-related gene (hERG) channel. The inhibition...

  • Increased myocardial oxidative stress

    [Mitochondrial complexes inhibition leading to left ventricular function decrease via increased myocardial oxidative stress] In accordance with the events outlined in the linear...
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