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Aryl Hydrocarbon Receptor Activation
Aryl Hydrocarbon Receptor Activation Data: The Target ID (CHEMBL3201) is assigned to Aryl Hydrocarbon Receptor (AHR) activation, so we collected all data related to this... -
hERG inhibition leading to cardiac toxicity
hERG channel blockade leading to sudden cardiac death Increased mortality triggered by drug-mediated blockade of human ether-a-gogo-related gene (hERG) channel. The inhibition... -
Increased myocardial oxidative stress
[Mitochondrial complexes inhibition leading to left ventricular function decrease via increased myocardial oxidative stress] In accordance with the events outlined in the linear...