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{
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{
            
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  "age_type": [],
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  "age_type": [],
            
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  "author": "Edoardo Luca Vigan\u00f2",
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  "author": "Edoardo Luca Vigan\u00f2",
            
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  "author_email": "edoardo.vigano@marionegri.it",
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  "author_email": "edoardo.vigano@marionegri.it",
            
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  "category": [],
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  "category": [],
            
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  "cells_number": "",
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  "cells_number": "",
            
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  "content": [],
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  "content": [],
            
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  "creator_user_id": "56153fff-4293-4f39-9723-fcc904de812a",
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  "creator_user_id": "56153fff-4293-4f39-9723-fcc904de812a",
            
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  "culture_medium": [],
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  "culture_medium": [],
            
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  "dimension": [],
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  "dimension": [],
            
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  "experiment_date": "",
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  "experiment_date": "",
            
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  "groups": [],
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  "groups": [],
            
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  "id": "ff91292e-d3d4-44ac-b081-3e040eee85d3",
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  "id": "ff91292e-d3d4-44ac-b081-3e040eee85d3",
            
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  "isopen": false,
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  "isopen": false,
            
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  "license_id": "",
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  "license_id": "",
            
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  "license_title": "",
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  "license_title": "",
            
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  "maintainer": "",
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  "maintainer": "",
            
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  "maintainer_email": "",
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  "maintainer_email": "",
            
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  "metadata_created": "2024-10-25T14:34:58.554350",
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  "metadata_created": "2024-10-25T14:34:58.554350",
            
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  "metadata_modified": "2024-10-25T14:36:41.470652",
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  "metadata_modified": "2024-10-25T14:36:43.134132",
            
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  "model": [],
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  "model": [],
            
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  "name": "apical-cardiotoxicity",
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  "name": "apical-cardiotoxicity",
            
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  "notes": "Drug-induced cardiotoxicity (DICT).\r\n\r\nBy utilizing 
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  "notes": "Drug-induced cardiotoxicity (DICT).\r\n\r\nBy utilizing 
            
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labeling documents for FDA (U.S. Food and Drug 
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labeling documents for FDA (U.S. Food and Drug 
            
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Administration)-approved drugs, is developed the largest dataset of 
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Administration)-approved drugs, is developed the largest dataset of 
            
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drugs annotated with ranked DICT risk in humans (DICTrank). 
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drugs annotated with ranked DICT risk in humans (DICTrank). 
            
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\r\nDICTrank categorizes drugs into four categories of DICT concerns 
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\r\nDICTrank categorizes drugs into four categories of DICT concerns 
            
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by integrating DICT severity and labeling content. \r\nThe dataset 
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by integrating DICT severity and labeling content. \r\nThe dataset 
            
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consists of 1318 drugs, classified as follows: Most-DICTConcern (341), 
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consists of 1318 drugs, classified as follows: Most-DICTConcern (341), 
            
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Less-DICT-Concern (528), No-DICT-Concern (343), and 
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Less-DICT-Concern (528), No-DICT-Concern (343), and 
            
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Ambiguous-DICTConcern (106; lacking sufficient information in the 
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Ambiguous-DICTConcern (106; lacking sufficient information in the 
            
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labeling document to determine cardiotoxicity potential). 
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labeling document to determine cardiotoxicity potential). 
            
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\r\n\r\nEndpoint: Multilabel\r\n\r\nData source: 
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\r\n\r\nEndpoint: Multilabel\r\n\r\nData source: 
            
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https://doi.org/10.1101/2023.07.06.548029",
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https://doi.org/10.1101/2023.07.06.548029",
            
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  "num_resources": 1,
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  "num_resources": 1,
            
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  "num_tags": 1,
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  "num_tags": 1,
            
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  "organization": {
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  "organization": {
            
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    "approval_status": "approved",
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    "approval_status": "approved",
            
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    "created": "2023-03-17T17:42:44.917090",
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    "created": "2023-03-17T17:42:44.917090",
            
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    "description": "The Mario Negri Institute for Pharmacological 
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    "description": "The Mario Negri Institute for Pharmacological 
            
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Research (www.marionegri.it) is a not-for-profit 
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Research (www.marionegri.it) is a not-for-profit 
            
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biomedical\r\nresearch organization.\r\nIt was established in Milan in 
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biomedical\r\nresearch organization.\r\nIt was established in Milan in 
            
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1961 and later (1984) opened research units in Bergamo, currently 
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1961 and later (1984) opened research units in Bergamo, currently 
            
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located at the\r\nKilometro Rosso Science and Technology Park, and 
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located at the\r\nKilometro Rosso Science and Technology Park, and 
            
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Ranica (near Bergamo)",
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Ranica (near Bergamo)",
            
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    "id": "e50db934-20d8-4a27-80a2-ce67bc4d99db",
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    "id": "e50db934-20d8-4a27-80a2-ce67bc4d99db",
            
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    "image_url": "2023-03-17-174244.890524IMNOrizzontaleRGB.png",
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    "image_url": "2023-03-17-174244.890524IMNOrizzontaleRGB.png",
            
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    "is_organization": true,
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    "is_organization": true,
            
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    "name": "irfmn",
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    "name": "irfmn",
            
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    "state": "active",
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    "state": "active",
            
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    "title": "IRFMN",
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    "title": "IRFMN",
            
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    "type": "organization"
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    "type": "organization"
            
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  },
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  },
            
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  "owner_org": "e50db934-20d8-4a27-80a2-ce67bc4d99db",
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  "owner_org": "e50db934-20d8-4a27-80a2-ce67bc4d99db",
            
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  "private": false,
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  "private": false,
            
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  "ratio_hipsccms_hcaecs": "",
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  "ratio_hipsccms_hcaecs": "",
            
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  "relationships_as_object": [],
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  "relationships_as_object": [],
            
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  "relationships_as_subject": [],
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  "relationships_as_subject": [],
            
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  "replicates_number": "",
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  "replicates_number": "",
            
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  "resources": [
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  "resources": [
            
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    {
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    {
            
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      "cache_last_updated": null,
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      "cache_last_updated": null,
            
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      "cache_url": null,
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      "cache_url": null,
            
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      "created": "2024-10-25T14:36:41.485272",
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      "created": "2024-10-25T14:36:41.485272",
            
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      "datastore_active": false,
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      "datastore_active": false,
            
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      "description": "QSAR-Ready database for Apical 
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      "description": "QSAR-Ready database for Apical 
            
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Cardiotoxicity.\r\n\r\nEndpoint multiclass: {2:Most-DICTConcern (341), 
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Cardiotoxicity.\r\n\r\nEndpoint multiclass: {2:Most-DICTConcern (341), 
            
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1:Less-DICT-Concern (528), 0:No-DICT-Concern (343)}",
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1:Less-DICT-Concern (528), 0:No-DICT-Concern (343)}",
            
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      "format": "CSV",
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      "format": "CSV",
            
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      "hash": "",
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      "hash": "",
            
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      "id": "059a7b4c-fdde-4a71-8726-283af5082893",
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      "id": "059a7b4c-fdde-4a71-8726-283af5082893",
            
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      "last_modified": "2024-10-25T14:36:41.446075",
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      "last_modified": "2024-10-25T14:36:41.446075",
            
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      "metadata_modified": "2024-10-25T14:36:41.475770",
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      "metadata_modified": "2024-10-25T14:36:43.139390",
            
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      "mimetype": null,
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      "mimetype": null,
            
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      "mimetype_inner": null,
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      "mimetype_inner": null,
            
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      "name": "Apical_cardiotoxicity_CDDD.csv",
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      "name": "Apical_cardiotoxicity_CDDD.csv",
            
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      "package_id": "ff91292e-d3d4-44ac-b081-3e040eee85d3",
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      "package_id": "ff91292e-d3d4-44ac-b081-3e040eee85d3",
            
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      "position": 0,
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      "position": 0,
            
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      "resource_type": null,
            
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      "size": 4903979,
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      "size": 4903979,
            
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      "state": "active",
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      "state": "active",
            
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      "url": 
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      "url": 
            
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-fdde-4a71-8726-283af5082893/download/apical_cardiotoxicity_cddd.csv",
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-fdde-4a71-8726-283af5082893/download/apical_cardiotoxicity_cddd.csv",
            
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      "url_type": "upload"
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      "url_type": "upload"
            
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    }
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    }
            
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  ],
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  ],
            
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  "size": 4903979,
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  "size": 4903979,
            
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  "state": "draft",
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  "state": "active",
            
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  "tags": [
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  "tags": [
            
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    {
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    {
            
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      "display_name": "Apical Cardiotoxicity",
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      "display_name": "Apical Cardiotoxicity",
            
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      "id": "3f3fe1a0-b7d2-4c0d-a0e2-5f0395df323f",
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      "id": "3f3fe1a0-b7d2-4c0d-a0e2-5f0395df323f",
            
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      "name": "Apical Cardiotoxicity",
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      "name": "Apical Cardiotoxicity",
            
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      "state": "active",
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      "state": "active",
            
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      "vocabulary_id": null
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      "vocabulary_id": null
            
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    }
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    }
            
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  ],
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  ],
            
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  "title": "Apical Cardiotoxicity",
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  "title": "Apical Cardiotoxicity",
            
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  "toxin": [],
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  "toxin": [],
            
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  "type": "dataset",
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  "type": "dataset",
            
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  "url": "",
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  "url": "",
            
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  "version": "0.1"
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  "version": "0.1"
            
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}
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}